Glycine
Amino acid taken before bed, often 2-3g, to help sleep onset
Sweet-tasting amino acid, around 2-3 grams in the evening. Small trials report faster sleep onset and better next-day alertness, possibly via a drop in core body temperature. Inexpensive, well tolerated, and so an add-on to sleep stacks rather than the centerpiece.
People on record
Sorted by strength of stance
Does it: documented as part of their own routine. Recommends: explicitly advises other people to do it. Discusses: covered it substantively without clear personal adoption; this can include criticism or disagreement.
- Andrew HubermanDoes it
Neuroscientist · Huberman Lab
Two grams of glycine goes into the evening list on three or four nights a week rather than every night.
Source: Huberman Lab: Toolkit for Sleep - Bryan JohnsonDoes it
Founder · Blueprint longevity protocol
1,200mg of glycine arrives in the morning Longevity Mix rather than as an evening sleep supplement.
Source: Blueprint: Longevity Mix
Aimed at the same thing
Other entries filed under sleep.
- Supplement$$$Cheap: Roughly under $50, or under $15/month.
Magnesium (threonate or glycinate)
Taken 30-60 minutes before bed to help with sleep onset
On record from 11 of 62 tracked people: 8 do it, 1 recommends it, 2 have discussed it - Supplement$$$Cheap: Roughly under $50, or under $15/month.
Melatonin
Widely sold as a sleeping aid; mostly a timing signal, not a sedative
On record from 4 of 62 tracked people: 1 recommends it, 3 have discussed it - Supplement$$$Cheap: Roughly under $50, or under $15/month.
Ashwagandha
Adaptogen used short-term to lower cortisol during stressful stretches
On record from 2 of 62 tracked people: 1 does it, 1 recommends it - Supplement$$$Cheap: Roughly under $50, or under $15/month.
L-theanine
Amino acid from tea used for calm focus, or with caffeine
On record from 2 of 62 tracked people: 2 do it - Supplement$$$Cheap: Roughly under $50, or under $15/month.
Apigenin
Chamomile-derived compound taken before bed, usually 50mg
On record from 1 of 62 tracked people: 1 does it - Supplement$$$Cheap: Roughly under $50, or under $15/month.
Myo-inositol
Taken before bed, often for getting back to sleep after waking
On record from 1 of 62 tracked people: 1 does it
Supplement entry · notes paraphrased from cited sources, quoted excerpts copied from the transcript they link to. Not medical advice. Not affiliated with, endorsed by, or reviewed by anyone listed. How this works.