Omega-3 (EPA/DHA)
Fish or algae oil, often 1-2g EPA daily
Peter Attia and Rhonda Patrick both test the omega-3 index rather than guessing at it. What they are testing is EPA and DHA from fish oil, or algae oil for people avoiding animal products, commonly taken at one to two grams of EPA a day, with interest in cardiovascular markers, triglycerides and mood. Freshness matters, since rancid oil is common.
People on record
Sorted by strength of stance
Does it: documented as part of their own routine. Recommends: explicitly advises other people to do it. Discusses: covered it substantively without clear personal adoption; this can include criticism or disagreement.
- Andrew HubermanDoes it
Neuroscientist · Huberman Lab
Treats omega-3s as foundational, and points to more than a gram of EPA a day for cardiovascular health, cognition and mood.
Source: Huberman Lab: supplementation topic page Exercise physiologist · Perform podcast
Puts his own fish oil habit at 15 years or more. Third-party testing for lead and mercury is what he checks first. He also warns that some brands pad a label with non-EPA and DHA oils to keep the fish oil count high and the active ingredients low. Momentous sponsors the podcast.
Source: Perform: Avoid Fitness Plateaus, Overtraining & Mis-Timed Performance Peaks- Bryan JohnsonDoes it
Founder · Blueprint longevity protocol
Algae-derived omega-3 fits the plant-based diet, at 400mg of EPA and 400mg of DHA.
Source: Blueprint: Omega-3 - Dave AspreyDoes it
Biohacker · Bulletproof Coffee
Favors krill oil over standard fish oil, on the argument that phospholipid-bound omega-3s reach the brain better. In his 2015 sleep short report he suggests taking it a couple of hours before bed and says it helps his own sleep.
Source: Bulletproof Radio Short Report #188: The Art and Science of Sleeping - Kelly StarrettDoes it
Doctor of physical therapy · The Ready State
Genetic testing showed him he does not process omega-3s well, so he doubled his dose to move the ratio at all. His 3 to 6 ratio was already inside normal limits, he says.
Source: The Tim Ferriss Show: Kelly Starrett Q&A, episode 85 transcript - Mark HymanDoes it
Physician · The Dr. Hyman Show · author of Young Forever
Daily fish oil, which he links to brain, mood and skin, and he credits it for his hard nails. He says he takes omega-3s himself and would rather see levels checked on a blood test than guessed at.
Source: The Dr. Hyman Show: How To Choose The Best Supplements (episode transcript) - Peter AttiaDoes it
Physician · The Drive · author of Outlive
EPA and DHA are in his own stack, and he recommends testing the omega-3 index rather than guessing at a dose.
Source: The Drive podcast - Rhonda PatrickDoes it
Biomedical scientist · FoundMyFitness
About two grams of fish oil a day, down from four because she eats a lot of salmon. She pushes people to test their omega-3 index rather than assume a dose is enough.
Source: FoundMyFitness: her 2025 supplement routine - Daniel AmenRecommends
Psychiatrist · Change Your Brain, Change Your Life
He says he thinks all of his patients should be on an omega-3 supplement, on the grounds that it helps calm inflammation. Inflammation, in his telling, is a major cause of both depression and dementia, and it gets its own letter in his memory mnemonic.
Source: Thirty Minute Mentors: Dr. Daniel Amen
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On record from 18 of 62 tracked people: 13 do it, 3 recommend it, 2 have discussed it
Supplement entry · notes paraphrased from cited sources, quoted excerpts copied from the transcript they link to. Not medical advice. Not affiliated with, endorsed by, or reviewed by anyone listed. How this works.