Vitamin K2
Usually taken alongside vitamin D for calcium handling
MK-7 is the form usually taken, alongside vitamin D, on the reasoning that this fat-soluble vitamin directs calcium to bone rather than arteries. Human outcome evidence is much weaker than the mechanistic story, so it stays a companion supplement rather than a headline one. Standing caution for anyone on blood thinners.
Who backs it
Sorted by strength of stance
- Bryan JohnsonDoes it
Founder · Blueprint longevity protocol
Taken alongside vitamin D in the daily stack for calcium handling and bone.
Source: Blueprint: Advanced Antioxidants - Rhonda PatrickDoes it
Biomedical scientist · FoundMyFitness
K2 goes alongside vitamin D in the fat-soluble vitamin group, for calcium handling and bone.
Source: FoundMyFitness: her 2025 supplement routine
Aimed at the same thing
Other entries filed under longevity.
- Supplement$$$Cheap: Roughly under $50, or under $15/month.
Protein powder
Whey or plant protein used to hit a daily protein target
Backed by 16 of 44 stacks: 11 do it, 3 recommend it, 2 have discussed it - Supplement$$$Cheap: Roughly under $50, or under $15/month.
Omega-3 (EPA/DHA)
Fish or algae oil, often 1-2g EPA daily
Backed by 7 of 44 stacks: 6 do it, 1 recommend it, 0 have discussed it - Supplement$$$Cheap: Roughly under $50, or under $15/month.
Multivitamin
Daily multivitamin and mineral taken as a nutritional backstop
Backed by 5 of 44 stacks: 4 do it, 1 recommend it, 0 have discussed it - Supplement$$$Cheap: Roughly under $50, or under $15/month.
Vitamin D3
Daily D3 through the darker months, usually paired with K2
Backed by 5 of 44 stacks: 4 do it, 1 recommend it, 0 have discussed it - Supplement$$$Mid: Roughly $50 to $500, or up to $50/month.
NMN and NAD precursors
Nicotinamide mononucleotide or riboside, taken to raise NAD+
Backed by 4 of 44 stacks: 3 do it, 0 recommend it, 1 have discussed it - Supplement$$$Mid: Roughly $50 to $500, or up to $50/month.Backed by 3 of 44 stacks: 3 do it, 0 recommend it, 0 have discussed it
Supplement entry · notes paraphrased from cited sources, quoted excerpts copied from the transcript they link to. Not medical advice. Not affiliated with, endorsed by, or reviewed by anyone listed. How this works.