Vitamin B12
The supplement plant-based stacks here treat as non-negotiable
B12 is only reliably available from animal foods or fortification, which is why a vegan or near-vegan diet is the standard case for supplementing it. Deficiency causes fatigue and irreversible nerve damage if left long enough. Older adults absorb it less well regardless of diet. Cheap, safe, and one of the few supplements here with an unambiguous case.
Who backs it
Sorted by strength of stance
- Rich RollDoes it
Ultra-endurance athlete · The Rich Roll Podcast
Supplements B12 as non-negotiable for eating fully plant-based, and says so plainly whenever the diet comes up.
Source: The Rich Roll Podcast - Rhonda PatrickRecommends
Biomedical scientist · FoundMyFitness
B12 is non-negotiable for anyone eating plant-based, she says, and absorption declines with age regardless of diet.
Source: FoundMyFitness
Aimed at the same thing
Other entries filed under energy or longevity.
- Supplement$$$Cheap: Roughly under $50, or under $15/month.
Multivitamin
Daily multivitamin and mineral taken as a nutritional backstop
Backed by 5 of 44 stacks: 4 do it, 1 recommend it, 0 have discussed it - Supplement$$$Cheap: Roughly under $50, or under $15/month.
Vitamin D3
Daily D3 through the darker months, usually paired with K2
Backed by 5 of 44 stacks: 4 do it, 1 recommend it, 0 have discussed it - Supplement$$$Mid: Roughly $50 to $500, or up to $50/month.
NMN and NAD precursors
Nicotinamide mononucleotide or riboside, taken to raise NAD+
Backed by 4 of 44 stacks: 3 do it, 0 recommend it, 1 have discussed it - Supplement$$$Mid: Roughly $50 to $500, or up to $50/month.Backed by 3 of 44 stacks: 3 do it, 0 recommend it, 0 have discussed it
- Supplement$$$Expensive: Several hundred dollars and up.
Bioniq personalized supplements
Bioniq
One daily granule formula built from your blood test results, adjusted over time
Backed by 1 of 44 stacks: 1 do it, 0 recommend it, 0 have discussed it - Protocol$$$Cheap: Roughly under $50, or under $15/month.
Resistance training
Lifting weights 2-4 times a week to build and hold muscle
Backed by 37 of 44 stacks: 32 do it, 3 recommend it, 2 have discussed it
Supplement entry · notes paraphrased from cited sources, quoted excerpts copied from the transcript they link to. Not medical advice. Not affiliated with, endorsed by, or reviewed by anyone listed. How this works.